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US sees record coronavirus infections as states face deadline for vaccine orders – The Guardian


Dec 5, 2020

  • More than 14m cases recorded with 2,607 deaths on Friday
  • Healthy people unlikely to be vaccinated before April – Fauci

As US states faced a deadline to place orders for a coronavirus vaccine, California went back into lockdown and federal authorities advised the wearing of masks indoors, new infections reached a record 227,885 on Friday.

Many states are reporting record infections, hospitalisations and deaths, with healthcare systems pushed to breaking point. The number of Americans hospitalised with Covid-19 hit an all-time high on Thursday, at 100,667.

The daily case average is 210,000 and deaths are averaging 1,800 per day, according to Johns Hopkins University, which recorded 2,607 deaths on Friday. The US has recorded more than 14m cases overall.

The alarming surge is in part attributed to millions choosing to travel and gather over the Thanksgiving holiday.

“People were less willing to change their behaviour than [on] any other day during the pandemic,” Laura Schewel, founder of StreetLight Data, an analytics firm, told the Associated Press.

As he continues to fruitlessly contest his conclusive presidential election defeat by Joe Biden, Donald Trump faces growing criticism for a perceived lack of leadership.

In advance of a federal Centers for Disease Control and Prevention (CDC) meeting next week that could green-light emergency authorisation of a vaccine produced by Pfizer, states have been advised of a Friday deadline to order for the two-stage jab.

On Saturday Dr James Hildreth, a member of the US Food and Drug Administration (FDA) vaccine advisory committee and the president and chief executive of Meharry Medical College, told NBC vaccinations could start soon after the crucial meeting.

“We’ll spend the day on Thursday reviewing the data from Pfizer and at the end of the day a vote will be taken,” he said. “So by the end of the day next Thursday, there could be a decision made about the vaccine.

“If the FDA commissioner decides to issue approval … on that day when the vote is taken, as early as Friday of next week we could see vaccinations happening across the country.”

The World Health Organization has warned governments and citizens not to drop their guard though a vaccination is close, saying healthcare systems could still buckle, and that recent data suggests that, though rare, reinfection is possible.

“We have seen the number of people infected continue to grow but we’re also seeing data emerge that protection may not be lifelong, and therefore we may see reinfections begin to occur,” Dr Mike Ryan, executive director of the WHO health emergencies program, told reporters in Geneva on Friday.

Britain has approved the Pfizer vaccine, raising hopes the tide could soon turn against a virus that has killed nearly 1.5 million around the world. But that too has come with controversy, after leading US expert Dr Anthony Fauci advanced then retracted an opinion that British authorities had not properly analysed data.

This May 4, 2020, file photo provided by the University of Maryland School of Medicine, shows the first patient enrolled in Pfizer’s COVID-19 coronavirus vaccine clinical trial at the University of Maryland School of Medicine in Baltimore. Photograph: AP

Fauci, a member of the White House taskforce, said on Friday healthy Americans should not expect to receive a vaccine until April, as healthcare workers, the elderly and people with chronic health conditions would be prioritised.

“A healthy non-elderly person with no recognisable underlying conditions will likely start … in the end of March, early April. Once you get into April, probably full blast with those individuals.” Fauci told CNN.

“The quicker you get the overwhelming majority of the country vaccinated the quicker you’re going to have that umbrella of herd immunity that will be so, so important to bringing the level of the virus way, way down.”

The first vaccine shipments are expected to be divided among states and federal agencies including the Department of Defense. That first effort will fall far short of protecting high-priority groups such as healthcare workers, a Reuters analysis found.

Writing for the Dispatch, a conservative magazine, Marty Makary, a Johns Hopkins professor, said the FDA must “adopt a sense of urgency”.

“We’ve had Operation Warp Speed in developing vaccines but Operation Turtle Speed in reviewing the results,” he wrote.

Experts have also warned that much is still unknown about vaccine candidates from Pfizer, Moderna and AstraZeneca, including the duration of immunity, possible long-term side effects and variance across ages, races and ethnicities.

On Thursday, Dr William Moss, the executive director of the International Vaccine Access Center at the Johns Hopkins Bloomberg School of Public Health, said it would probably take another year or so to understand what the vaccines can do.

“It will be important to continue to follow up with individuals who get the vaccine,” he said. “Other vaccines … may turn out to be even better.”

Not enough time has elapsed to determine whether the vaccines have long-term side effects or can prevent transmission, Moss said, adding: “We’ll only know the short-term side effects.”

Rupali Limaye, the director of behavioural and implementation science at the International Vaccine Access Center, said Covid vaccines will not save lives if a majority of the public refuses to take them. It is currently estimated that up to 70% of the US population must be vaccinated for herd immunity to take effect.

Healthcare officials must therefore begin identifying potential barriers to widespread vaccination, including trust disparities between white and non-white populations, Limaye said.

“There has to be messaging to address issues such as hesitancy, so that appropriate intervention can be applied,” she said. “It must be tailored to meet different audiences and it must be credible and transparent.”












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